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877864-04-5

877864-04-5 structure
877864-04-5 structure
  • Name: THP-SS-alcohol
  • Chemical Name: THP-SS-alcohol
  • CAS Number: 877864-04-5
  • Molecular Formula: C9H18O3S2
  • Molecular Weight: 238.367
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-07 23:37:46
  • Modify Date: 2024-01-11 08:33:55
  • THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name THP-SS-alcohol
Synonyms 2-{[2-(Tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethanol
Ethanol, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]-
MFCD28505568
Description THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.2±0.1 g/cm3
Boiling Point 369.8±42.0 °C at 760 mmHg
Molecular Formula C9H18O3S2
Molecular Weight 238.367
Flash Point 177.4±27.9 °C
Exact Mass 238.069733
LogP 1.57
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.547