1011268-28-2
1011268-28-2 structure
- Name: Biotin-PEG2-C4-alkyne
- Chemical Name: Biotin-PEG2-C4-Alkyne
- CAS Number: 1011268-28-2
- Molecular Formula: C22H36N4O5S
- Molecular Weight: 468.610
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-21 17:55:52
- Modify Date: 2024-04-03 14:24:24
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Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | Biotin-PEG2-C4-Alkyne |
|---|---|
| Synonyms |
MFCD28505539
N-(2-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}ethyl)-5-hexynamide 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-[2-[2-[2-[(1-oxo-5-hexyn-1-yl)amino]ethoxy]ethoxy]ethyl]-, (3aS,4S,6aR)- |
| Description | Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 799.8±60.0 °C at 760 mmHg |
| Molecular Formula | C22H36N4O5S |
| Molecular Weight | 468.610 |
| Flash Point | 437.5±32.9 °C |
| Exact Mass | 468.240631 |
| LogP | -0.60 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.523 |
| Storage condition | 2-8°C |