1225057-68-0

1225057-68-0 structure

Name: TAMRA-PEG4-Alkyne
Chemical Name: TAMRA-PEG4-alkyne
CAS Number: 1225057-68-0
Molecular Formula: C₃₆H₄₁N₃O₈
Molecular Weight: 643.73
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-04 18:04:22
Modify Date: 2024-01-09 19:11:33
TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TAMRA-PEG4-alkyne
Synonyms	MFCD28505543

Description	TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562