1282040-14-5

1282040-14-5 structure
1282040-14-5 structure
  • Name: 3'-Azido-3'-deoxy-5-methylcytidine
  • Chemical Name: 3'-Azido-3'-deoxy-5-methylcytidine
  • CAS Number: 1282040-14-5
  • Molecular Formula: C10H14N6O4
  • Molecular Weight: 282.26
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2018-06-23 08:44:04
  • Modify Date: 2024-01-02 12:01:05
  • 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1].

Name 3'-Azido-3'-deoxy-5-methylcytidine
Description 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1].
Related Catalog
Target

HIV-1:0.06 μM (EC50, in PBM cells)

XMRV:43.5 μM (CC50, in MCF-7 cells)

References

[1]. Singh IR, et al. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One. 2010 Apr 1;5(4):e9948.

Molecular Formula C10H14N6O4
Molecular Weight 282.26
Storage condition 2-8°C