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1352221-63-6

1352221-63-6 structure
1352221-63-6 structure
  • Name: S-acetyl-PEG6
  • Chemical Name: S-acetyl-PEG6-alcohol
  • CAS Number: 1352221-63-6
  • Molecular Formula: C14H28O7S
  • Molecular Weight: 340.433
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-08 15:16:40
  • Modify Date: 2024-01-10 05:53:52
  • S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-PEG6-alcohol
Synonyms S-(17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ethanethioate
Ethanethioic acid, S-(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ester
MFCD22574786
Description S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 441.7±45.0 °C at 760 mmHg
Molecular Formula C14H28O7S
Molecular Weight 340.433
Flash Point 220.9±28.7 °C
Exact Mass 340.155579
LogP -1.41
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.480