141410-98-2

141410-98-2 structure

141410-98-2 structure

Name: Edobacomab
Chemical Name: Edobacomab
CAS Number: 141410-98-2
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Infection
Create Date: 2018-12-02 18:17:03
Modify Date: 2024-04-05 19:06:37
Edobacomab (E5) is a mouse anti-endotoxin monoclonal IgM antibody. Edobacomab ca be uesd for the research of sepsis caused by Gram-negative bacterial infections[1].

Name	Edobacomab

Description	Edobacomab (E5) is a mouse anti-endotoxin monoclonal IgM antibody. Edobacomab ca be uesd for the research of sepsis caused by Gram-negative bacterial infections[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
In Vitro	Prolgolimab can bind endotoxin and neutralize it with subsequent attenuate inflammatory response and improved outcome[2].
References	[1]. Kobayashi H, et, al. [Phase I study of edobacomab (E5) in patients with gram-negative sepsis]. Kansenshogaku Zasshi. 1994 Jan;68(1):59-80. [2]. Angus DC, et, al. E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators. JAMA. 2000 Apr 5;283(13):1723-30.

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