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1433996-83-8

1433996-83-8 structure
1433996-83-8 structure
  • Name: Ald-Ph-PEG5-Boc
  • Chemical Name: Ald-Ph-PEG5-t-butyl ester
  • CAS Number: 1433996-83-8
  • Molecular Formula: C22H34O8
  • Molecular Weight: 426.501
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-20 05:55:24
  • Modify Date: 2024-01-23 19:17:11
  • Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-Ph-PEG5-t-butyl ester
Synonyms ALD-PH-PEG5-CH2CH2COOTBU
Description Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 521.3±50.0 °C at 760 mmHg
Molecular Formula C22H34O8
Molecular Weight 426.501
Flash Point 222.5±30.2 °C
Exact Mass 426.225372
LogP 1.79
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.500