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1446282-37-6

1446282-37-6 structure
1446282-37-6 structure
  • Name: Bromo-PEG5-phosphonic acid
  • Chemical Name: Bromo-PEG5-phosphonic acid
  • CAS Number: 1446282-37-6
  • Molecular Formula: C12H26BrO8P
  • Molecular Weight: 409.21
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-09 19:17:57
  • Modify Date: 2024-09-12 11:31:32
  • Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG5-phosphonic acid
Synonyms MFCD25424102
Description Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H26BrO8P
Molecular Weight 409.21