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1446282-39-8

1446282-39-8 structure
1446282-39-8 structure
  • Name: Thiol-PEG3-Boc
  • Chemical Name: Thiol-PEG3-t-butyl ester
  • CAS Number: 1446282-39-8
  • Molecular Formula: C13H26O5S
  • Molecular Weight: 294.41
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-05 07:09:33
  • Modify Date: 2024-01-02 17:01:11
  • Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Thiol-PEG3-t-butyl ester
Synonyms THIOL-PEG3-T-BUTYL ESTER
Description Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H26O5S
Molecular Weight 294.41