1581248-63-6

1581248-63-6 structure

Name: Tos-PEG3-CH2COOH
Chemical Name: Tos-PEG4-CH2CO2H
CAS Number: 1581248-63-6
Molecular Formula: C₁₅H₂₂O₈S
Molecular Weight: 362.395
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-08 10:06:20
Modify Date: 2025-08-26 22:23:56
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG4-CH2CO2H
Synonyms	MFCD27977516 Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]- {2-[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]ethoxy}acetic acid

Description	Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.