1612192-28-5

1612192-28-5 structure

Name: 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose
Chemical Name: 3-Deoxy-3-fluoro-D-ribofuranose 1,2-diacetate 5-(4-methylbenzoate)
CAS Number: 1612192-28-5
Molecular Formula: C₁₇H₁₉FO₇
Molecular Weight: 354.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-03 23:09:12
Modify Date: 2024-04-03 13:20:29
1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3-Deoxy-3-fluoro-D-ribofuranose 1,2-diacetate 5-(4-methylbenzoate)
Synonyms	1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methylbenzoyl)-β-D-glycero-pentofuranose β-D-glycero-Pentofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate)

Description	1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.