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1802907-91-0

1802907-91-0 structure
1802907-91-0 structure

Name Methyltetrazine-PEG4-Acid
Synonyms 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-
MFCD28334558
1-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12-tetraoxapentadecan-15-oic acid
Description Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 647.6±65.0 °C at 760 mmHg
Molecular Formula C20H28N4O7
Molecular Weight 436.459
Flash Point 345.5±34.3 °C
Exact Mass 436.195801
LogP -0.70
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.533
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