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1807501-85-4

1807501-85-4 structure
1807501-85-4 structure
  • Name: endo-BCN-PEG2-alcohol
  • Chemical Name: endo-BCN-PEG2-alcohol
  • CAS Number: 1807501-85-4
  • Molecular Formula: C17H27NO5
  • Molecular Weight: 325.400
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-07 00:15:00
  • Modify Date: 2024-01-08 17:16:34
  • endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name endo-BCN-PEG2-alcohol
Synonyms Carbamic acid, N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]-, (1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl {2-[2-(2-hydroxyethoxy)ethoxy]ethyl}carbamate
MFCD27977489
Description endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 496.9±30.0 °C at 760 mmHg
Molecular Formula C17H27NO5
Molecular Weight 325.400
Flash Point 254.3±24.6 °C
Exact Mass 325.188934
LogP 0.91
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.528