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1807505-35-6

1807505-35-6 structure
1807505-35-6 structure
  • Name: m-PEG5-sulfonic acid
  • Chemical Name: m-PEG5-sulfonic acid
  • CAS Number: 1807505-35-6
  • Molecular Formula: C11H24O8S
  • Molecular Weight: 316.368
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-05 16:37:21
  • Modify Date: 2024-01-09 10:47:08
  • m-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG5-sulfonic acid
Synonyms MFCD28976653
2,5,8,11,14-Pentaoxahexadecane-16-sulfonic acid
Description m-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Molecular Formula C11H24O8S
Molecular Weight 316.368
Exact Mass 316.119202
LogP -3.31
Index of Refraction 1.465