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1807512-37-3

1807512-37-3 structure
1807512-37-3 structure
  • Name: THP-SS-PEG1-Tos
  • Chemical Name: THP-SS-PEG1-Tos
  • CAS Number: 1807512-37-3
  • Molecular Formula: C16H24O5S3
  • Molecular Weight: 392.554
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-12 06:52:47
  • Modify Date: 2024-01-05 15:42:59
  • THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name THP-SS-PEG1-Tos
Synonyms Ethanol, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]-, 4-methylbenzenesulfonate
2-{[2-(Tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethyl 4-methylbenzenesulfonate
MFCD28950768
Description THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.3±0.1 g/cm3
Boiling Point 539.4±50.0 °C at 760 mmHg
Molecular Formula C16H24O5S3
Molecular Weight 392.554
Flash Point 280.0±30.1 °C
Exact Mass 392.078583
LogP 3.58
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.586