1807512-41-9
1807512-41-9 structure
- Name: 1,1,1-Trifluoroethyl-PEG4-alcohol
- Chemical Name: 1,1,1-Trifluoroethyl-PEG5-Alcohol
- CAS Number: 1807512-41-9
- Molecular Formula: C10H19F3O5
- Molecular Weight: 276.250
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-05 23:32:25
- Modify Date: 2024-01-09 21:59:09
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1,1,1-Trifluoroethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1,1,1-Trifluoroethyl-PEG5-Alcohol |
|---|---|
| Synonyms |
3,6,9,12-Tetraoxatetradecan-1-ol, 14,14,14-trifluoro-
MFCD28950755 14,14,14-Trifluoro-3,6,9,12-tetraoxatetradecan-1-ol |
| Description | 1,1,1-Trifluoroethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 324.8±37.0 °C at 760 mmHg |
| Molecular Formula | C10H19F3O5 |
| Molecular Weight | 276.250 |
| Flash Point | 152.6±23.0 °C |
| Exact Mass | 276.118469 |
| LogP | -1.10 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.407 |