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1807512-42-0

1807512-42-0 structure
1807512-42-0 structure
  • Name: m-PEG5-phosphonic acid ethyl ester
  • Chemical Name: m-PEG5-phosphonic acid ethyl ester
  • CAS Number: 1807512-42-0
  • Molecular Formula: C15H33O8P
  • Molecular Weight: 372.39
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-06 10:05:58
  • Modify Date: 2024-01-12 13:13:01
  • m-PEG5-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG5-phosphonic acid ethyl ester
Synonyms MFCD28950773
Description m-PEG5-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H33O8P
Molecular Weight 372.39