1807518-71-3
1807518-71-3 structure
- Name: Hydroxy-PEG3-NHS
- Chemical Name: Hydroxy-PEG3-NHS
- CAS Number: 1807518-71-3
- Molecular Formula: C13H21NO8
- Molecular Weight: 319.308
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-15 09:36:51
- Modify Date: 2024-01-10 14:03:59
-
Hydroxy-PEG3-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Hydroxy-PEG3-NHS |
|---|---|
| Synonyms |
2,5-Pyrrolidinedione, 1-[3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-1-oxopropoxy]-
1-[(3-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione MFCD26793742 |
| Description | Hydroxy-PEG3-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 458.0±55.0 °C at 760 mmHg |
| Molecular Formula | C13H21NO8 |
| Molecular Weight | 319.308 |
| Flash Point | 230.8±31.5 °C |
| Exact Mass | 319.126709 |
| LogP | -3.23 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.509 |