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1807530-11-5

1807530-11-5 structure
1807530-11-5 structure
  • Name: Propargyl-PEG4-methylamine
  • Chemical Name: Propargyl-PEG4-methylamine
  • CAS Number: 1807530-11-5
  • Molecular Formula: C12H23NO4
  • Molecular Weight: 245.315
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-09 01:15:18
  • Modify Date: 2024-01-09 22:01:22
  • Propargyl-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-methylamine
Synonyms PROPARGYL-PEG4-MEA
Description Propargyl-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.0±0.1 g/cm3
Boiling Point 317.1±32.0 °C at 760 mmHg
Molecular Formula C12H23NO4
Molecular Weight 245.315
Flash Point 136.2±14.6 °C
Exact Mass 245.162704
LogP -0.87
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.452