1807534-86-6
1807534-86-6 structure
- Name: 3,4-Dibromo-Mal-PEG2-Amine TFA
- Chemical Name: 3,4-Dibromo-Mal-PEG2-Amine
- CAS Number: 1807534-86-6
- Molecular Formula: C10H14Br2N2O4
- Molecular Weight: 386.037
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-09 15:08:35
- Modify Date: 2024-01-09 21:58:45
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3,4-Dibromo-Mal-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3,4-Dibromo-Mal-PEG2-Amine |
|---|---|
| Synonyms |
1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-3,4-dibromo-
1-{2-[2-(2-Aminoethoxy)ethoxy]ethyl}-3,4-dibromo-1H-pyrrole-2,5-dione MFCD27635180 |
| Description | 3,4-Dibromo-Mal-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 425.1±45.0 °C at 760 mmHg |
| Molecular Formula | C10H14Br2N2O4 |
| Molecular Weight | 386.037 |
| Flash Point | 210.9±28.7 °C |
| Exact Mass | 383.932007 |
| LogP | -0.21 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.602 |