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1807537-33-2

1807537-33-2 structure
1807537-33-2 structure
  • Name: Bromoacetamido-PEG3-C2-Boc
  • Chemical Name: Bromoacetamido-PEG3-t-Butyl Ester
  • CAS Number: 1807537-33-2
  • Molecular Formula: C15H28BrNO6
  • Molecular Weight: 398.290
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-09 02:56:01
  • Modify Date: 2024-01-14 14:38:48
  • Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromoacetamido-PEG3-t-Butyl Ester
Synonyms 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oate
MFCD28505521
6,9,12-Trioxa-3-azapentadecan-15-oic acid, 1-bromo-2-oxo-, 1,1-dimethylethyl ester
Description Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.3±0.1 g/cm3
Boiling Point 507.6±50.0 °C at 760 mmHg
Molecular Formula C15H28BrNO6
Molecular Weight 398.290
Flash Point 260.8±30.1 °C
Exact Mass 397.109985
LogP 0.74
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.477