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1807537-38-7

1807537-38-7 structure
1807537-38-7 structure
  • Name: Aminooxy-PEG4-acid
  • Chemical Name: Aminoxy-PEG4-acid
  • CAS Number: 1807537-38-7
  • Molecular Formula: C11H23NO7
  • Molecular Weight: 281.303
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-18 19:34:50
  • Modify Date: 2024-01-02 23:10:25
  • Aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Aminoxy-PEG4-acid
Synonyms 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-(aminooxy)-
MFCD28015778
1-(Aminooxy)-3,6,9,12-tetraoxapentadecan-15-oic acid
Description Aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 448.6±45.0 °C at 760 mmHg
Molecular Formula C11H23NO7
Molecular Weight 281.303
Flash Point 225.1±28.7 °C
Exact Mass 281.147461
LogP -1.49
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.468