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1807539-01-0

1807539-01-0 structure
1807539-01-0 structure
  • Name: Boc-Aminooxy-PEG4-Tos
  • Chemical Name: t-Boc-Aminoxy-PEG4-Tos
  • CAS Number: 1807539-01-0
  • Molecular Formula: C20H33NO9S
  • Molecular Weight: 463.542
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-17 22:28:37
  • Modify Date: 2024-01-23 15:17:00
  • Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Boc-Aminoxy-PEG4-Tos
Synonyms Carbamic acid, N-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
MFCD28064335
2,2-Dimethyl-4-oxo-3,6,9,12,15-pentaoxa-5-azaheptadecan-17-yl 4-methylbenzenesulfonate
Description Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Molecular Formula C20H33NO9S
Molecular Weight 463.542
Exact Mass 463.187592
LogP 2.09
Index of Refraction 1.500
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