Name | Acid-PEG4-t-butyl ester |
---|---|
Synonyms |
MFCD28096679
Bis(2-methyl-2-propanyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(1,1-dimethylethyl) ester |
Description | Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1]. |
---|---|
Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
Density | 1.0±0.1 g/cm3 |
---|---|
Boiling Point | 452.9±35.0 °C at 760 mmHg |
Molecular Formula | C16H30O8 |
Molecular Weight | 406.511 |
Flash Point | 191.1±26.0 °C |
Exact Mass | 406.256653 |
LogP | 1.84 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.450 |
Storage condition | 2-8°C |