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1835759-85-7

1835759-85-7 structure
1835759-85-7 structure
  • Name: Acid-PEG4-C2-Boc
  • Chemical Name: Acid-PEG4-t-butyl ester
  • CAS Number: 1835759-85-7
  • Molecular Formula: C16H30O8
  • Molecular Weight: 406.511
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-16 08:06:20
  • Modify Date: 2024-01-10 10:57:24
  • Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1].

Name Acid-PEG4-t-butyl ester
Synonyms MFCD28096679
Bis(2-methyl-2-propanyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(1,1-dimethylethyl) ester
Description Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Jennifer PITZEN , et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

Density 1.0±0.1 g/cm3
Boiling Point 452.9±35.0 °C at 760 mmHg
Molecular Formula C16H30O8
Molecular Weight 406.511
Flash Point 191.1±26.0 °C
Exact Mass 406.256653
LogP 1.84
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.450
Storage condition 2-8°C