183745-81-5

183745-81-5 structure

Name: Amyloid β-Protein (1-15) trifluoroacetate salt
Chemical Name: AMYLOID BETA-PROTEIN (1-15)
CAS Number: 183745-81-5
Molecular Formula: C₇₈H₁₀₇N₂₅O₂₇
Molecular Weight: 1826.85
Catalog: Peptides
Create Date: 2018-06-18 09:30:30
Modify Date: 2024-01-08 12:27:54
β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

Name	AMYLOID BETA-PROTEIN (1-15)
Synonyms	β-Amyloid (1-15)

Description	β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Amyloid-β Research Areas >> Neurological Disease Peptides
Target	Amyloid-β[1]
In Vitro	β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].
References	[1]. Portelius E, et al. Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease. J Alzheimers Dis. 2012;31(2):335-41.