Name | Acid-PEG9-NHS ester |
---|---|
Synonyms |
31-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-31-oxo-4,7,10,13,16,19,22,25,28-nonaoxahentriacontan-1-oic acid
MFCD28064339 4,7,10,13,16,19,22,25,28-Nonaoxahentriacontan-1-oic acid, 31-[(2,5-dioxo-1-pyrrolidinyl)oxy]-31-oxo- Acid-dPEG(R)9-NHS ester |
Description | Acid-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.3±0.1 g/cm3 |
---|---|
Boiling Point | 685.1±65.0 °C at 760 mmHg |
Molecular Formula | C26H45NO15 |
Molecular Weight | 611.633 |
Flash Point | 368.1±34.3 °C |
Exact Mass | 611.278931 |
LogP | -4.86 |
Vapour Pressure | 0.0±4.6 mmHg at 25°C |
Index of Refraction | 1.503 |