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2055044-68-1

2055044-68-1 structure
2055044-68-1 structure
  • Name: Boc-NH-PEG7-acid
  • Chemical Name: Boc-NH-PEG7-CH2CH2COOH
  • CAS Number: 2055044-68-1
  • Molecular Formula: C22H43NO11
  • Molecular Weight: 497.577
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-14 02:44:51
  • Modify Date: 2024-01-09 16:25:46
  • Boc-NH-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG7-CH2CH2COOH
Synonyms 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26-octaoxa-5-azanonacosan-29-oic acid
MFCD29052162
3,8,11,14,17,20,23,26-Octaoxa-5-azanonacosan-29-oic acid, 2,2-dimethyl-4-oxo-
Description Boc-NH-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 598.4±50.0 °C at 760 mmHg
Molecular Formula C22H43NO11
Molecular Weight 497.577
Flash Point 315.7±30.1 °C
Exact Mass 497.283600
LogP -1.22
Vapour Pressure 0.0±3.7 mmHg at 25°C
Index of Refraction 1.468