218441-99-7

218441-99-7 structure

Name: BDNF(human)
Chemical Name: BRAIN DERIVED NEUROTROPHIC FACTOR, HUMAN
CAS Number: 218441-99-7
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Trk Receptor
Create Date: 2018-06-10 07:55:43
Modify Date: 2024-01-01 20:40:15
BDNF (human) is a neurotrophin in the central nervous system and mediates survival and differentiation of neurons. BDNF (human) binds to TrkB and leads to the dimerization and autophosphorylation of tyrosine residues in the intracellular domain of the receptor. BDNF (human) can be used for study of neurodegenerative and psychiatric disorder[1][2].

Name	BRAIN DERIVED NEUROTROPHIC FACTOR, HUMAN
Synonyms	REC BRAIN-DERIVED NEUROTROPHIC FACTOR (HUMAN)

Description	BDNF (human) is a neurotrophin in the central nervous system and mediates survival and differentiation of neurons. BDNF (human) binds to TrkB and leads to the dimerization and autophosphorylation of tyrosine residues in the intracellular domain of the receptor. BDNF (human) can be used for study of neurodegenerative and psychiatric disorder[1][2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor Research Areas >> Neurological Disease
Target	IC50: TrkB[1]
References	[1]. Robert H Lipsky, et al. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Ann N Y Acad Sci [2]. A Cattaneo, et al. The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders. Transl Psychiatry

Storage condition	−20°C

WGK Germany	3