688360-06-7

688360-06-7 structure

Name: Xanthohumol I
Chemical Name: Xanthohumol I
CAS Number: 688360-06-7
Molecular Formula: C₂₁H₂₂O₆
Molecular Weight: 370.4
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2019-01-21 17:35:22
Modify Date: 2025-08-30 14:52:53
Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1].

Name	Xanthohumol I

Description	Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Neuronal Signaling >> AChE
Target	AChE BChE
References	[1]. Orhan IE, et al. Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives. Phytomedicine. 2018 Mar 15;42:25-33.