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782475-35-8

782475-35-8 structure
782475-35-8 structure
  • Name: Bromo-PEG3-Acid
  • Chemical Name: Bromo-PEG3-Acid
  • CAS Number: 782475-35-8
  • Molecular Formula: C9H17BrO5
  • Molecular Weight: 285.13228
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-01 01:12:43
  • Modify Date: 2024-01-03 17:26:24
  • Bromo-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG3-Acid
Synonyms Bromo-PEG3-C2-acid
Description Bromo-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C9H17BrO5
Molecular Weight 285.13228