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874208-90-9

874208-90-9 structure
874208-90-9 structure
  • Name: m-PEG6-Boc
  • Chemical Name: m-PEG7-t-butyl ester
  • CAS Number: 874208-90-9
  • Molecular Formula: C20H40O9
  • Molecular Weight: 424.526
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-10-31 20:04:46
  • Modify Date: 2024-01-10 10:51:46
  • m-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name m-PEG7-t-butyl ester
Synonyms 2-Methyl-2-propanyl 2,5,8,11,14,17,20-heptaoxatricosan-23-oate
MFCD28950751
2,5,8,11,14,17,20-Heptaoxatricosan-23-oic acid, 1,1-dimethylethyl ester
Description m-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.0±0.1 g/cm3
Boiling Point 467.7±40.0 °C at 760 mmHg
Molecular Formula C20H40O9
Molecular Weight 424.526
Flash Point 197.2±27.4 °C
Exact Mass 424.267242
LogP -0.73
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.447