Name | G3-C12 |
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Description | G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. |
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Related Catalog | |
Target |
Kd: 88 nM (Galectin-3)[1] |
In Vitro | G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1]. |
References |
Molecular Formula | C74H115N23O23S2 |
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Molecular Weight | 1758.98 |
Storage condition | 2-8℃ |