2166387-65-9

2166387-65-9 structure

Name: BI-3802
Chemical Name: BI-3802
CAS Number: 2166387-65-9
Molecular Formula: C₂₄H₂₉ClN₆O₃
Molecular Weight: 484.98
Catalog: Research Areas Cancer
Create Date: 2018-08-15 11:26:17
Modify Date: 2024-01-13 16:26:47
BI-3802 is a highly potent BCL6 degrader, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3802 has antitumor activity.

Name	BI-3802

Description	BI-3802 is a highly potent BCL6 degrader, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3802 has antitumor activity.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	IC50: ≤3 nM (BCL6 BTB)[1]
In Vitro	BI-3802 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3802 shows an IC50 of 43 nM for the cellular BCL6[1].
References	[1]. Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.