1262770-67-1

1262770-67-1 structure

Name: PropionylproMazine-D6 hydrochloride
Chemical Name: PropionylproMazine-D6 hydrochloride
CAS Number: 1262770-67-1
Molecular Formula: C₂₀H₁₉D₆ClN₂OS
Molecular Weight: 382.980
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2019-01-20 02:28:34
Modify Date: 2024-01-11 18:17:11
Propionylpromazine-d6 hydrochloride is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].

Name	PropionylproMazine-D6 hydrochloride
Synonyms	1-[10-(3-{Bis[(2H3)methyl]amino}propyl)-10H-phenothiazin-2-yl]-1-propanone hydrochloride (1:1) 1-Propanone, 1-[10-[3-(dimethyl-d3-amino)propyl]-10H-phenothiazin-2-yl]-, hydrochloride (1:1)

Description	Propionylpromazine-d6 hydrochloride is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tyers, Mike, et al. Method for treating a brain cancer with ifenprodil. US8058243.

RIDADR	NONH for all modes of transport