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912367-45-4

912367-45-4 structure
912367-45-4 structure

Name CHK1-IN-2
Description CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.
Related Catalog
Target

Chk1:6 nM (IC50)

In Vitro CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM, which is a potential cancer therapeutic that can be utilized for enhancing the efficacy of DNA damaging agents[1].
References

[1]. Yang B, et al. Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J Med Chem. 2018 Feb 8;61(3):1061-1073.

Molecular Formula C20H22N4OS
Molecular Weight 366.48
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