Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GNE 2861
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Purity: 98.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: GNE-2861
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: GNE-2861
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
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1394121-05-1

1394121-05-1 structure

1394121-05-1 structure

Name: GNE 2861
Chemical Name: PAK-IN-1
CAS Number: 1394121-05-1
Molecular Formula: C₂₂H₂₆N₆O₂
Molecular Weight: 406.48
Catalog: Signaling Pathways Cell Cycle/DNA Damage PAK
Create Date: 2019-02-11 16:34:29
Modify Date: 2024-09-19 17:33:04
PAK-IN-1 is a PAK inhibitor that displays group II selectivity. PAK-IN-1 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively.

Name	PAK-IN-1

Description	PAK-IN-1 is a PAK inhibitor that displays group II selectivity. PAK-IN-1 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PAK Signaling Pathways >> Cytoskeleton >> PAK Research Areas >> Cancer
Target	IC50: 7.5 nM (PAK4), 36 nM (PAK5), 126 nM (PAK6)[1]
In Vitro	PAK-IN-1 is compound 4 from the reference[1].
References	[1]. Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem Lett. 2015 May 22;6(7):776-81.

Molecular Formula	C₂₂H₂₆N₆O₂
Molecular Weight	406.48