Name | PI3K/mTOR Inhibitor-2 |
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Description | PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR[1]. Antitumor activity[1]. |
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Related Catalog | |
Target |
PI3Kα:3.4 nM (IC50) PI3Kβ:34 nM (IC50) PI3Kδ:16 nM (IC50) PI3Kγ:1 nM (IC50) mTOR:4.7 nM (IC50) |
In Vitro | PI3K/mTOR Inhibitor-2 (Compound 31) inhibits p-AKT and p-p70s6k in MCF-7 cells with IC50s of 11.6 and 89.2 nM, respectively[1]. |
References |
Molecular Formula | C20H13ClF2N4O4S |
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Molecular Weight | 478.86 |