1115270-63-7

1115270-63-7 structure

Name: IAXO-102
Chemical Name: IAXO-102
CAS Number: 1115270-63-7
Molecular Formula: C₃₅H₇₁NO₅
Molecular Weight: 585.94
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2019-03-30 21:07:34
Modify Date: 2025-08-25 17:00:20
IAXO-102 is a TLR4 antagonist, inhibits MAPK and p65 NF-kB phosphorylation involved in down regulation of the expression of TLR4 and TLR4 dependent proinflammatory protein. IAXO-102 prevents experimental abdominal aortic aneurysm development[1].

Name	IAXO-102

Description	IAXO-102 is a TLR4 antagonist, inhibits MAPK and p65 NF-kB phosphorylation involved in down regulation of the expression of TLR4 and TLR4 dependent proinflammatory protein. IAXO-102 prevents experimental abdominal aortic aneurysm development[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer
Target	TLR4
References	[1]. Huggins C, et al. A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis. 2015 Oct;242(2):563-70.

Molecular Formula	C₃₅H₇₁NO₅
Molecular Weight	585.94