1802525-61-6

1802525-61-6 structure

Name: LRRK2 inhibitor 1
Chemical Name: LRRK2 inhibitor 1
CAS Number: 1802525-61-6
Molecular Formula: C₂₀H₂₃N₅O₄
Molecular Weight: 397.43
Catalog: Signaling Pathways Autophagy LRRK2
Create Date: 2019-03-30 19:09:33
Modify Date: 2024-01-09 14:40:19
LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8 nM.

Name	LRRK2 inhibitor 1

Description	LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8 nM.
Related Catalog	Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Neurological Disease
Target	pIC50: 6.8 nM (LRRK2)[1]
References	[1]. Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620.