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1853254-97-3

1853254-97-3 structure

1853254-97-3 structure

Name: PEN-221
Chemical Name: PEN-221
CAS Number: 1853254-97-3
Molecular Formula: C₈₃H₁₀₉ClN₁₄O₂₀S₄
Molecular Weight: 1786.55
Catalog: Signaling Pathways GPCR/G Protein Somatostatin Receptor
Create Date: 2019-03-30 19:20:33
Modify Date: 2025-08-25 18:49:24
PEN-221 is a Somatostatin receptor 2 (SSTR2)-targeting cytotoxic conjugate with an IC50 of 10 nM.

Name	PEN-221

Description	PEN-221 is a Somatostatin receptor 2 (SSTR2)-targeting cytotoxic conjugate with an IC50 of 10 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor
Target	IC50: 10 nM (SSTR2)[1]
References	[1]. White BH, et al. Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo. J Med Chem. 2019 Mar 14;62(5):2708-2719.

Molecular Formula	C₈₃H₁₀₉ClN₁₄O₂₀S₄
Molecular Weight	1786.55

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