Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclophilin inhibitor 1
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
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1509904-96-4

1509904-96-4 structure

1509904-96-4 structure

Name: Cyclophilin inhibitor 1
Chemical Name: Cyclophilin inhibitor 1
CAS Number: 1509904-96-4
Molecular Formula: C₃₁H₃₉N₅O₇
Molecular Weight: 593.67
Catalog: Signaling Pathways Anti-infection HCV
Create Date: 2019-06-01 18:31:00
Modify Date: 2024-01-09 12:24:47
Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].

Name	Cyclophilin inhibitor 1

Description	Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection
Target	Kd: 5 nM (Cyclophilin A)[1] EC50: 98 nM (HCV 2a)[1]
In Vitro	Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM[1].
References	[1]. Mackman RL, et al. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 8;61(21):9473-9499.

Molecular Formula	C₃₁H₃₉N₅O₇
Molecular Weight	593.67

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