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2093388-45-3

2093388-45-3 structure
2093388-45-3 structure
  • Name: E3 Ligand-Linker Conjugate 4
  • Chemical Name: E3 ligase Ligand 9
  • CAS Number: 2093388-45-3
  • Molecular Formula: C18H23N3O3
  • Molecular Weight: 329.39
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2019-06-02 10:39:56
  • Modify Date: 2024-01-02 08:57:44
  • E3 ligase Ligand 9 is a Ligand of BETd-260 for E3 Ligase used in PROTAC. BETd-260 is a potent BET degrader based on PROTAC technology, with an IC50 of 51 pM against BRD4 protein in RS4;11 leukemia cell line[1].

Name E3 ligase Ligand 9
Description E3 ligase Ligand 9 is a Ligand of BETd-260 for E3 Ligase used in PROTAC. BETd-260 is a potent BET degrader based on PROTAC technology, with an IC50 of 51 pM against BRD4 protein in RS4;11 leukemia cell line[1].
Related Catalog
Target

E3 ligase[1].

References

[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

Molecular Formula C18H23N3O3
Molecular Weight 329.39
Storage condition 2-8℃