2222355-77-1

2222355-77-1 structure

2222355-77-1 structure

Name: SNIPER(ABL)-024
Chemical Name: SNIPER(ABL)-024
CAS Number: 2222355-77-1
Molecular Formula: C₅₂H₆₁F₃N₈O₉S
Molecular Weight: 1031.15
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2019-06-01 19:44:12
Modify Date: 2024-01-10 17:48:11
SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM[1].

Name	SNIPER(ABL)-024

Description	SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
References	[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula	C₅₂H₆₁F₃N₈O₉S
Molecular Weight	1031.15