2222354-18-7

2222354-18-7 structure
2222354-18-7 structure
  • Name: SNIPER(ABL)-033
  • Chemical Name: SNIPER(ABL)-033
  • CAS Number: 2222354-18-7
  • Molecular Formula: C61H73F3N10O9S2
  • Molecular Weight: 1211.42
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
  • Create Date: 2019-06-01 20:20:10
  • Modify Date: 2025-08-25 11:08:05
  • SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].

Name SNIPER(ABL)-033
Description SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].
Related Catalog
References

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula C61H73F3N10O9S2
Molecular Weight 1211.42
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