2222354-18-7

2222354-18-7 structure

2222354-18-7 structure

Name: SNIPER(ABL)-033
Chemical Name: SNIPER(ABL)-033
CAS Number: 2222354-18-7
Molecular Formula: C₆₁H₇₃F₃N₁₀O₉S₂
Molecular Weight: 1211.42
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2019-06-01 20:20:10
Modify Date: 2024-01-21 19:42:12
SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].

Name	SNIPER(ABL)-033

Description	SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
References	[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula	C₆₁H₇₃F₃N₁₀O₉S₂
Molecular Weight	1211.42