2140260-89-3

2140260-89-3 structure

Name: SNIPER(ABL)-062
Chemical Name: SNIPER(ABL)-062
CAS Number: 2140260-89-3
Molecular Formula: C₅₃H₆₃ClF₂N₁₀O₉S
Molecular Weight: 1089.64
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2019-06-01 11:29:57
Modify Date: 2024-01-11 11:10:04
SNIPER(ABL)-062, in which an ABL inhibitor is linked to a ligand of cIAP1 via a linker containing a variable polyethylene glycol (PEG) unit, shows a potent activity to degrade the BCR-ABL protein[1].

Name	SNIPER(ABL)-062

Description	SNIPER(ABL)-062, in which an ABL inhibitor is linked to a ligand of cIAP1 via a linker containing a variable polyethylene glycol (PEG) unit, shows a potent activity to degrade the BCR-ABL protein[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
References	[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula	C₅₃H₆₃ClF₂N₁₀O₉S
Molecular Weight	1089.64