2230810-28-1

2230810-28-1 structure

2230810-28-1 structure

Name: Tuberculosis inhibitor 1
Chemical Name: Tuberculosis inhibitor 1
CAS Number: 2230810-28-1
Molecular Formula: C₃₄H₃₇N₅O₃
Molecular Weight: 563.69
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2019-06-29 20:33:05
Modify Date: 2024-01-08 18:45:27
Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1].

Name	Tuberculosis inhibitor 1

Description	Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	EC50: 5 nM (Trypanosoma brucei)[1]
In Vitro	Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1].
References	[1]. Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692.

Molecular Formula	C₃₄H₃₇N₅O₃
Molecular Weight	563.69