Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VU6001376
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: VU6001376
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: VU6001376
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1968546-34-0

1968546-34-0 structure

1968546-34-0 structure

Name: VU6001376
Chemical Name: VU6001376
CAS Number: 1968546-34-0
Molecular Formula: C₁₈H₁₄F₂N₆OS
Molecular Weight: 400.41
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2019-06-30 20:15:14
Modify Date: 2025-08-29 10:47:56
VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM[1].

Name	VU6001376

Description	VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGlu4:50.1 nM (EC50)
References	[1]. Bollinger SR, et al. Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu4). J Med Chem. 2019 Jan 10;62(1):342-358.

Molecular Formula	C₁₈H₁₄F₂N₆OS
Molecular Weight	400.41

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