2093416-31-8

2093416-31-8 structure

Name: E3 ligase Ligand-Linker Conjugates 30
Chemical Name: E3 ligase Ligand-Linker Conjugates 30
CAS Number: 2093416-31-8
Molecular Formula: C₂₁H₂₈N₄O₇
Molecular Weight: 448.47
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2019-08-04 07:23:59
Modify Date: 2025-08-27 09:42:33
E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrader[1].

Name	E3 ligase Ligand-Linker Conjugates 30

Description	E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.

Molecular Formula	C₂₁H₂₈N₄O₇
Molecular Weight	448.47