1612782-86-1
1612782-86-1 structure
- Name: UNC2541
- Chemical Name: UNC2541
- CAS Number: 1612782-86-1
- Molecular Formula: C24H34FN7O2
- Molecular Weight: 471.57
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK TAM Receptor
- Create Date: 2019-08-03 17:03:59
- Modify Date: 2024-01-12 17:30:57
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UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM)[1].
| Name | UNC2541 |
|---|
| Description | UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM)[1]. |
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| Related Catalog | |
| Target |
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl (IC50, 120 nM), Tyro3 (IC50, 220 nM) and Flt3 (IC50, 320 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM)[1]. |
| References |
| Molecular Formula | C24H34FN7O2 |
|---|---|
| Molecular Weight | 471.57 |