2001571-40-8

2001571-40-8 structure

Name: eCF-309
Chemical Name: eCF309
CAS Number: 2001571-40-8
Molecular Formula: C₁₈H₂₁N₇O₃
Molecular Weight: 383.404
Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
Create Date: 2019-09-07 11:57:16
Modify Date: 2024-01-10 12:22:02
eCF309 is a potent and highly selective mTOR inhibitor with remarkably low off-target activities (IC50 = 10-15 nM, both in vitro and in cells)[1].

Name	eCF309
Synonyms	2-Benzoxazolamine, 5-[4-amino-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]- 3-(2-Amino-1,3-benzoxazol-5-yl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Description	eCF309 is a potent and highly selective mTOR inhibitor with remarkably low off-target activities (IC50 = 10-15 nM, both in vitro and in cells)[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
References	[1]. Craig Fraser, et al. eCF309: a potent, selective and cell-permeable mTOR inhibitor. Med. Chem. Commun., 2016, 7, 471-477.